Endometrial ablation is commonly used to treat heavy menstrual bleeding in an outpatient setting without the need for general anesthesia. This device design is intended to accommodate a variety of uterine sizes using a uniform balloon configuration. This study aims to evaluate how the size, shape, and placement of the three inflatable balloons on the probe interact with anatomical variations among patients. The work includes an in-depth analysis of anatomical data and the statistical distribution of uterus and cervix dimensions within the population. A SolidWorks Flow Simulation was developed to model the uterus, cervix, and probe interaction, providing a robust tool to investigate how changes in balloon geometry affect mass flow rate. To complement the simulations, a physical testing model of the uterus was constructed, incorporating interchangeable cervical canal inserts. This model supports experimental evaluation of various probe designs across a spectrum of anatomical sizes. Final recommendations based on insights gained through statistical analysis, computational simulation, and experimental validation were provided to the sponsor of this project.